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James R Sellers Selected Research

Stroke (Strokes)

1/2021Myosin-Specific Adaptations of In vitro Fluorescence Microscopy-Based Motility Assays.
8/2014Chaperone-enhanced purification of unconventional myosin 15, a molecular motor specialized for stereocilia protein trafficking.
3/2013Mammalian myosin-18A, a highly divergent myosin.
1/2013Kinetic characterization of nonmuscle myosin IIb at the single molecule level.
5/2010Direct observation of the myosin-Va power stroke and its reversal.
9/2008Direct observation of the mechanochemical coupling in myosin Va during processive movement.
1/2008Kinetics of ADP dissociation from the trail and lead heads of actomyosin V following the power stroke.
10/2005The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head.
9/2005Load-dependent kinetics of myosin-V can explain its high processivity.
12/2002The prepower stroke conformation of myosin V.
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James R Sellers Research Topics

Disease

11Stroke (Strokes)
01/2021 - 01/2002
2MYH9-Related Disorders
01/2020 - 11/2002
2Arthrogryposis renal dysfunction cholestasis syndrome
01/2019 - 12/2017
1Deafness (Deaf Mutism)
01/2021
1Thrombocytopenia (Thrombopenia)
01/2020
1Fibrosarcoma
11/2016
1Intracranial Aneurysm (Cerebral Aneurysm)
01/2015
1Rupture
01/2015
1Central Nervous System Cavernous Hemangioma
01/2015
1Hearing Loss (Hearing Impairment)
08/2014
1Arthrogryposis
08/2013
1Muscular Diseases (Myopathy)
08/2013
1Heart Diseases (Heart Disease)
05/2013
1Blindness (Hysterical Blindness)
04/2008
1Usher Syndromes (Usher Syndrome)
04/2008
1Nonsyndromic Deafness
04/2008
1Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
01/2003

Drug/Important Bio-Agent (IBA)

7Myosins (Myosin)IBA
01/2021 - 01/2002
4Actins (F Actin)IBA
01/2021 - 09/2005
3Adenosine Triphosphatases (ATPase)IBA
01/2021 - 01/2002
3Myosin Type VIBA
09/2005 - 01/2002
2Nonmuscle Myosin Type IIAIBA
01/2020 - 11/2002
2ActomyosinIBA
08/2013 - 01/2008
2Adenosine Triphosphate (ATP)IBA
03/2013 - 09/2008
1Proteins (Proteins, Gene)FDA Link
01/2019
1rho-Associated KinasesIBA
01/2015
1DEET (DET)IBA
08/2014
1myosin-binding protein CIBA
08/2013
1Cardiac MyosinsIBA
05/2013
1Myosin SubfragmentsIBA
01/2013
1NucleotidesIBA
04/2008
1Myosin VIIaIBA
04/2008
1Adenosine Diphosphate (ADP)IBA
01/2008
1Ventricular MyosinsIBA
01/2003
1Myosin Type IIIBA
12/2002